CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity

S Sinha, GN Jha, P Anand, T Qidwai, SS Pati… - Human immunology, 2009 - Elsevier
Complement receptor 1 (CR1/CD35) levels on erythrocytes and related CR1 polymorphisms
have been associated with response to falciparum malaria in populations inhabiting malaria-
endemic regions. Differences in disease association profiles of its low expression alleles
have been observed in populations from different regions of the world. We analyzed the
influence of CR1 levels and associated SNPs on susceptibility/resistance to falciparum
malaria in Indian populations. Two CR1 SNPs [exon 22 (A/G) and intron 27 (A/T)] define the …

CR1 levels and gene polymorphisms exhibit differential association with falciparum malaria in regions of varying disease endemicity.

SS Swapnil Sinha, GN Jha, PA Prerna Anand… - 2009 - cabidigitallibrary.org
Abstract Complement receptor 1 (CR1/CD35) levels on erythrocytes and related CR1
polymorphisms have been associated with response to falciparum malaria in populations
inhabiting malaria-endemic regions. Differences in disease association profiles of its low
expression alleles have been observed in populations from different regions of the world.
We analyzed the influence of CR1 levels and associated SNPs on susceptibility/resistance
to falciparum malaria in Indian populations. Two CR1 SNPs [exon 22 (A/G) and intron 27 …
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