Calcium oxalate stone formation occurs under pathological conditions and accounts for
more than 80% of all types of kidney stones. In the current study, we show for the first time
that calcium oxalate stones are formed in the mouse inner ear of a genetic model for hearing
loss and vestibular dysfunction in humans. The vestibular system within the inner ear is
dependent on extracellular tiny calcium carbonate minerals for proper function. Thousands
of these biominerals, known as otoconia, are associated with the utricle and saccule sensory …