In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this
species asymptomatically colonizes many areas of the body, particularly the gastrointestinal
and genitourinary tracts of healthy individuals. Alterations in host immunity, stress, resident
microbiota, and other factors can lead to C. albicans overgrowth, causing a wide range of
infections, from superficial mucosal to hematogenously disseminated candidiasis. To date …