Candida antarctica lipase B-catalyzed synthesis of acetamides using [BMIm (PF6)] as a reaction medium
An efficient protocol has been developed for synthesis of acetamides using Candida
antarctica lipase B (CaL B) in [BMIm (PF6)] as a greener reaction medium. The reaction is
applicable to a wide variety of aliphatic esters/acetic acid and amines providing excellent
yields of corresponding acetamide. The catalyst exhibits remarkable activity and is reusable
for up to four consecutive cycles.
antarctica lipase B (CaL B) in [BMIm (PF6)] as a greener reaction medium. The reaction is
applicable to a wide variety of aliphatic esters/acetic acid and amines providing excellent
yields of corresponding acetamide. The catalyst exhibits remarkable activity and is reusable
for up to four consecutive cycles.
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