Cardiac Steatosis in Diabetes Mellitus: A 1H-Magnetic Resonance Spectroscopy Study

JM McGavock, I Lingvay, I Zib, T Tillery, N Salas… - Circulation, 2007 - Am Heart Assoc
Background—The risk of heart failure in type 2 diabetes mellitus is greater than can be
accounted for by hypertension and coronary artery disease. Rodent studies indicate that in
obesity and type 2 diabetes mellitus, lipid overstorage in cardiac myocytes produces
lipotoxic intermediates that cause apoptosis, which leads to heart failure. In humans with
diabetes mellitus, cardiac steatosis previously has been demonstrated in explanted hearts of
patients with end-stage nonischemic cardiomyopathy. Whether cardiac steatosis precedes …

[引用][C] Cardiac steatosis in diabetes mellitus: a^ 1H-magnetic resonance spectroscopy study

M JM - Circulation, 2007 - cir.nii.ac.jp
Cardiac steatosis in diabetes mellitus : a ^1H-magnetic resonance spectroscopy study |
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