… As shown in this work, treatment with carnosine in a dose of 10mg/kg/day,ip used for six
successive days prior to doxorubicin receiving has effectively reduced the acute kidney
damage caused by injection of one dosage of doxorubicin (15mg/kg,ip) in mice. A remarkable
elaboration in the disordered biochemical parameters (increased serum blood urea and
creatinine levels, as well as renal cortical MDA level, with decrease levels of kidney GSH,
catalase and SOD activities) could be considered as a good clue for carnosine protective …