Carotid intima-media thickness progression as surrogate marker for cardiovascular risk: meta-analysis of 119 clinical trials involving 100 667 patients
Background: To quantify the association between effects of interventions on carotid intima-
media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk.
Methods: We systematically collated data from randomized, controlled trials. cIMT was
assessed as the mean value at the common-carotid-artery; if unavailable, the maximum
value at the common-carotid-artery or other cIMT measures were used. The primary
outcome was a combined CVD end point defined as myocardial infarction, stroke …
media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk.
Methods: We systematically collated data from randomized, controlled trials. cIMT was
assessed as the mean value at the common-carotid-artery; if unavailable, the maximum
value at the common-carotid-artery or other cIMT measures were used. The primary
outcome was a combined CVD end point defined as myocardial infarction, stroke …
Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients
M Sweeting - 2020 - figshare.le.ac.uk
Background: To quantify the association between effects of interventions on carotid
intimamedia thickness (cIMT) progression and their effects on cardiovascular disease (CVD)
risk. Methods: We systematically collated data from randomized controlled trials. cIMT was
assessed as the mean value at the common-carotid-artery; if unavailable, the maximum
value at the common-carotid-artery or other cIMT measures were utilized. The primary
outcome was a combined CVD endpoint defined as myocardial infarction, stroke …
intimamedia thickness (cIMT) progression and their effects on cardiovascular disease (CVD)
risk. Methods: We systematically collated data from randomized controlled trials. cIMT was
assessed as the mean value at the common-carotid-artery; if unavailable, the maximum
value at the common-carotid-artery or other cIMT measures were utilized. The primary
outcome was a combined CVD endpoint defined as myocardial infarction, stroke …
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