Changes in treatment adherence and glycemic control during the transition to adolescence in type 1 diabetes
JR Rausch, KK Hood, A Delamater… - Diabetes …, 2012 - Am Diabetes Assoc
Diabetes care, 2012•Am Diabetes Assoc
OBJECTIVE To test models of unidirectional and bidirectional change between treatment
adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND
METHODS We conducted a 2-year longitudinal, multisite study of 225 youth with type 1
diabetes recruited at the cusp of adolescence (aged 9–11 years) to describe the mutual
influences of glycemic control as measured by HbA1c and treatment adherence as
measured by blood glucose monitoring frequency (BGMF) during the transition to …
adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND
METHODS We conducted a 2-year longitudinal, multisite study of 225 youth with type 1
diabetes recruited at the cusp of adolescence (aged 9–11 years) to describe the mutual
influences of glycemic control as measured by HbA1c and treatment adherence as
measured by blood glucose monitoring frequency (BGMF) during the transition to …
OBJECTIVE
To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes.
RESEARCH DESIGN AND METHODS
We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9–11 years) to describe the mutual influences of glycemic control as measured by HbA1c and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence.
RESULTS
HbA1c increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA1c. A change (increase) in HbA1c was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates.
CONCLUSIONS
The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.
Am Diabetes Assoc
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