Characterization of the translationally controlled tumor protein (TCTP) interactome reveals novel binding partners in human cancer cells
Translationally controlled tumor protein (TCTP) is a highly conserved housekeeping protein
present in eukaryotic organisms. It is involved in regulating many fundamental processes
and plays a critical role in tumor reversion and tumorigenesis. Increasing evidence suggests
that TCTP plays a role in the regulation of cell fate determination and is a promising
therapeutic target for cancer. To decipher the exact mechanisms by which TCTP functions
and how all these functions are integrated, we analyzed the interactome of TCTP in HeLa …
present in eukaryotic organisms. It is involved in regulating many fundamental processes
and plays a critical role in tumor reversion and tumorigenesis. Increasing evidence suggests
that TCTP plays a role in the regulation of cell fate determination and is a promising
therapeutic target for cancer. To decipher the exact mechanisms by which TCTP functions
and how all these functions are integrated, we analyzed the interactome of TCTP in HeLa …
[引用][C] Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer Cells
L Siting, C Minghai, X Qian, Z Jia, C Zongqiang… - 2016
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