过去一年中添加的文章,按日期排序

Allogeneic CAR-T cells for cancer immunotherapy

X Chen, Y Gao, Y Zhang - Immunotherapy, 2024 - Taylor & Francis
2 天前 - chimeric antigen receptor (CAR)-modified T (CAR-T) cell … Up to now, 11 autologous
CAR-T cell products have been … However, the application of autologous CAR-T cell therapy …

Silencing of SIRPα enhances the antitumor efficacy of CAR-M in solid tumors

…, Z Zhao, C Shi, L Shan, A Yang, T Wang - Cellular & Molecular …, 2024 - nature.com
3 天前 - … to nontumor cells remain substantial. Here, we engineered chimeric antigen
receptor … and eliminate tumor cells, the mechanism differs from that of CAR-T cells. Therefore, …

Peptide-guided adaptor-CAR T-Cell therapy for the treatment of SSTR2-expressing neuroendocrine tumors

C Pellegrino, N Favalli, L Volta, R Benz… - …, 2024 - Taylor & Francis
6 天前 - … Another immunotherapeutic option against SSTR2-positive NETs might be
chimeric antigen receptor T-cells (CAR T-cells). CAR T-cells are T-cells expressing, via genetic …

Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses

S Yang, M Sheffer, IE Kaplan, Z Wang… - Nature …, 2024 - nature.com
7 天前 - engineered to display human DR18 potently activated mesothelin-targeting chimeric
antigen receptor (CAR) NK cells … blockade, chimeric antigen receptor (CAR) T cells, CAR …

for specific gene delivery

T Schaser, CJ Buchholz - … and Manufacturing of CAR T cells, 2024 - books.google.com
8 天前 - … KG, Bergisch Gladbach, Germany, 4Frankfurt Cancer Institute, Goethe University,
Frankfurt am Main, Germany Chimeric antigen receptor (CAR)-expressing T cells are a …

[PDF][PDF] TCR-engineered T cells in the era of CAR T cells: seeking the best of both orlds

TL Wachsmann - 2024 - scholarlypublications …
9 天前 - … Cellular therapy using chimeric antigen receptor (CAR-) engineered T cells can
be effective in the treatment of refractory B-cell and plasma cell malignancies. Despite high …

Therapeutic targets of armored chimeric antigen receptor T cells navigating the tumor microenvironment

X Li, T Chen, X Li, H Zhang, Y Li, S Zhang… - … Hematology & Oncology, 2024 - Springer
10 天前 - Chimeric antigen receptor (CAR) T cellChimeric antigen receptor (CAR) T cell
therapy involves the genetic modification of T cells to recognize and bind to specific cancer cell

Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia

RJ Ji, GH Cao, WQ Zhao, MY Wang, P Gao, YZ Zhang… - Cell Stem Cell, 2024 - cell.com
10 天前 - Immunotherapy using chimeric antigen receptor T (CAR-T) cell therapy or antibody-drug
… Animals infused with CAR-T cells exhibited a reduced tumor burden compared with …

Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion

S Fiorenza, Y Zheng, J Purushe, TJ Bock… - Nature …, 2024 - nature.com
14 天前 - … to dysfunction, hence their utilities as starting T cell products for manufacturing
adoptive cellular immunotherapy 1 . Chimeric antigen receptor (CAR)-modified T cell (CAR-T) …

[HTML][HTML] Survival advantage of native and engineered T cells is acquired by mitochondrial transfer from mesenchymal stem cells

E Parra-Crisóstomo… - Journal of …, 2024 - … -medicine.biomedcentral.com
14 天前 - Chimeric antigen receptor T (CAR-T) cell therapy, approved for hematologic cancers,
retains … , including CAR T-cell susceptibility to apoptosis. Therefore, strategies to improve …