[HTML][HTML] Chromatin: liquid or solid?
A Zidovska - Cell, 2020 - cell.com
… of chromatin fibers in solid-like and liquid-like states. Bottom inset depicts solid-like
chromatin fibers (blue lines) that serve as a scaffold for nucleation of phase-separated liquid …
chromatin fibers (blue lines) that serve as a scaffold for nucleation of phase-separated liquid …
[HTML][HTML] The solid and liquid states of chromatin
… that can result in solid or liquid chromatin condensates depending on … chromatin and specific
chromatin-associated proteins and relate this in vitro behavior to the properties of chromatin …
chromatin-associated proteins and relate this in vitro behavior to the properties of chromatin …
[HTML][HTML] Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells
… interactions between chromatin fibers. Our results reveal that condensed chromatin exists in
a solid-… a scaffold that supports liquid-liquid phase separation of chromatin binding proteins. …
a solid-… a scaffold that supports liquid-liquid phase separation of chromatin binding proteins. …
[HTML][HTML] Chromatin liquid–liquid phase separation (LLPS) is regulated by ionic conditions and fiber length
… of chromatin in the cell nucleus is crucial for maintaining cellular homeostasis. Chromatin can
exist in solid- or liquid… suggested that chromatin undergoes liquid–liquid phase separation (…
exist in solid- or liquid… suggested that chromatin undergoes liquid–liquid phase separation (…
Condensed but liquid-like domain organization of active chromatin regions in living human cells
… Our findings resolve the discrepancy of whether chromatin is liquid-like (38) or solid-like (7).
Both reports are consistent with our results. It is very reasonable that the FRAP experiments, …
Both reports are consistent with our results. It is very reasonable that the FRAP experiments, …
[HTML][HTML] Liquid-like behavior of chromatin
… discussed liquid-like chromatin behaviors as local chromatin structure and dynamics. Next,
we examine higher-order chromatin structures. It has been long known that chromatin forms …
we examine higher-order chromatin structures. It has been long known that chromatin forms …
[HTML][HTML] Fluid-like chromatin: Toward understanding the real chromatin organization present in the cell
… have drastically shifted our view on chromatin from a static regular structure to a more …
chromatin organization inside the cell. Here we critically discuss our current view on chromatin …
chromatin organization inside the cell. Here we critically discuss our current view on chromatin …
Liquid–liquid phase separation in chromatin
K Rippe - Cold Spring Harbor perspectives in biology, 2022 - cshperspectives.cshlp.org
… At the same time, the folding of chromatin in the nucleus … chromatin organization, chromatin
binding, and LLPS is discussed by comparing and contrasting three prototypical chromatin …
binding, and LLPS is discussed by comparing and contrasting three prototypical chromatin …
In diverse conditions, intrinsic chromatin condensates have liquid-like material properties
… between liquid-like and solid-like behavior of chromatin … rely on dynamic rearrangements of
chromatin. Whether such … as in a liquid-like state) or require input of energy (as in a solid-like …
chromatin. Whether such … as in a liquid-like state) or require input of energy (as in a solid-like …
[HTML][HTML] Liquid-like chromatin in the cell: What can we learn from imaging and computational modeling?
… , chromatin is considered ‘liquid-like’ rather than a solid-like … Indeed, such liquid-like chromatin
condensates were … 23] and that chromatin condensates appear to have a solid-like feature …
condensates were … 23] and that chromatin condensates appear to have a solid-like feature …