Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi
TCL de Jesus, VS Nunes, MC Lopes… - Journal of proteome …, 2016 - ACS Publications
Histones are well-conserved proteins that form the basic structure of chromatin in eukaryotes
and undergo several post-translational modifications, which are important for the control of
transcription, replication, DNA damage repair, and chromosome condensation. In early
branched organisms, histones are less conserved and appear to contain alternative sites for
modifications, which could reveal evolutionary unique functions of histone modifications in
gene expression and other chromatin-based processes. Here, by using high-resolution …
and undergo several post-translational modifications, which are important for the control of
transcription, replication, DNA damage repair, and chromosome condensation. In early
branched organisms, histones are less conserved and appear to contain alternative sites for
modifications, which could reveal evolutionary unique functions of histone modifications in
gene expression and other chromatin-based processes. Here, by using high-resolution …
[引用][C] Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi
NV Santana, LM de Camargo, MD Evelin, IL Kei… - 2016
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