过去一年中添加的文章,按日期排序

HIF-2α Inhibition Disrupts Leukemia Stem Cell Metabolism and Impairs Vascular Microenvironment to Enhance Chronic Myeloid Leukemia Treatment

J Wang, W Ma, J Huang, G Qiu, T Zhang, Q Wei, C He… - Cancer Letters, 2024 - Elsevier
25 天前 - … (CML) contribute to treatment resistance and disease recurrence. Metabolism
regulates … after tyrosine kinase inhibitor (TKI) treatment. Deletion of HIF-2α suppresses disease

Myocardial Infarction in Chronic Myeloid Leukemia: Results from the Nationwide Readmission Database

MKJSM Yassinf - 2024 - karger.com
27 天前 - … Introduction: Chronic myeloid leukemia (CML) is a hema… the introduction of different
tyrosine kinase inhibitors (TKIs), … As a result, coronary artery disease is anticipated to be the …

Cardiovascular complications associated with asciminib use: A retrospective analysis.

S Savani, A Pawa, H Mahadevia, SR Master - 2024 - ascopubs.org
40 天前 - … In comparison to Ponatinib (tyrosine kinase inhibitor) which is … Chronic Myeloid
leukemia (CML) between 2018-2023. Cardiovascular events such as coronary artery disease (…

[HTML][HTML] Repurposing pexmetinib as an inhibitor of TKI-resistant BCR:: ABL1

D Fontana, F Malighetti, M Villa, A Zambon… - Leukemia, 2024 - nature.com
54 天前 - Chronic myeloid leukemia (CML) is a clonal disorder … other tyrosine kinase inhibitors
(TKIs) targeting the ABL1 … is associated with serious cardiovascular adverse events [4], and …

Ponatinib‐review of historical development, current status, and future research

HM Kantarjian, HT Chifotides… - American journal of …, 2024 - Wiley Online Library
59 天前 - … -generation BCR::ABL1 tyrosine kinase inhibitor (TKI) with … for T315I-mutated chronic
myeloid leukemia (CML), CML … risk of toxicities, including cardiovascular risks. Ponatinib-…

[PDF][PDF] A Targetable Receptor Tyrosine Kinase in Metastatic Pheochromocytoma and Paraganglioma: A Future Journey for Anlotinib?

H Alkaissi, K Pacak - Journal of the Endocrine Society, 2024 - academic.oup.com
63 天前 - … role, the first tyrosine kinase inhibitor (TKI), in treating chronic myelogenous leukemia
[2]. … As the molecular underpinnings of PPGL are being unraveled, a clear role of vascular

Myocardial Infarction in Chronic Myeloid Leukemia: Results from Nationwide Readmission Database

EA Ali, N Patel, M Khalid, R Kaddoura, M Kalavar… - Oncology, 2024 - karger.com
66 天前 - Chronic myeloid leukemia (CML) is a hematological … and the introduction of different
tyrosine kinase inhibitors (TKI), … As a result, coronary artery disease is anticipated to be the …

Transformer Based Deep Learning Method Reveals Novel Drugs and Comorbidity Associations in Pulmonary Arterial Hypertension

V Kolli, J Gomez-Arroyo, M Gu, JM Elwing… - … VASCULAR …, 2024 - atsjournals.org
69 天前 - … Drugs showing emerging PAH association included other tyrosine kinase inhibitors
- … inhibitor bortezomib (probability: 0.8-0.9, p <0.0001). Chronic Myeloid Leukemia (CML) …

Known Complication With Unknown Mechanism: Dasatinib Induced Pleural Effusion

RN Tiperneni, E Hamric, S Christy… - A50. ALL ABOUT …, 2024 - atsjournals.org
69 天前 - tyrosine kinase inhibitor approved for first-line treatment of Philadelphia-positive
chronic myelogenous leukemia (… , skin rash, cardiac or autoimmune disease history, and age of …

Role of MAPK11 in the protective mechanisms against toxicity of tyrosine kinase inhibitors

AP Hnatiuk, D Staudt, M Mercola - Cancer Research, 2024 - AACR
109 天前 - … TKI ponatinib as a paradigm of cardiac toxicity. Ponatinib has … Chronic Myeloid
Leukemia (CML) due to T315I-ABL1 mutation, and has been associated with high risk of cardiac