[HTML][HTML] Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection

MG Schrauder, R Strick, R Schulz-Wendtland… - PloS one, 2012 - journals.plos.org
Introduction MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules
with relevance as regulators of gene expression thereby affecting crucial processes in
cancer development. MiRNAs offer great potential as biomarkers for cancer detection due to
their remarkable stability in blood and their characteristic expression in many different
diseases. We investigated whether microarray-based miRNA profiling on whole blood could
discriminate between early stage breast cancer patients and healthy controls. Methods We …

[PDF][PDF] Circulating Micro-RNAs as Potential Blood-Based Markers for Early

MG Schrauder, R Strick, R Schulz-Wendtland… - 2012 - academia.edu
Abstract Introduction: MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA
molecules with relevance as regulators of gene expression thereby affecting crucial
processes in cancer development. MiRNAs offer great potential as biomarkers for cancer
detection due to their remarkable stability in blood and their characteristic expression in
many different diseases. We investigated whether microarray-based miRNA profiling on
whole blood could discriminate between early stage breast cancer patients and healthy …
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