Introduction: The high rate of autoagressive action in patients with psychotic symptoms manifested during the beginning of active psychopharmatherapy, and they are often the reason for psychiatric help. The continuous growth of autoagressive behavior indicates the number of unsolved problems in clinical suicidology. Aim: The aim of this research was to explore the clinical and psychopathological characteristics of the autoagressive behavior in patients with the first psychotic episode with considering circadian rhythms.

Material and Methods: There was a research in regional clinical psychiatric hospital and 130 patients were involved in the research with autoagressive behavior during the first psychotic episodes. Clinical and psychopathological, psychodiagnostic and statistical methods were used. Characteristic clinical manifestations of first psychotic episode is determined by PANSS [1986] and BPRS [1962], level of suicidal risk is determined by Lyuban-Plotstsa’s scale [2000], characteristics of biological rhythms is established by Estberg’s questionnaire [1986].

Results: Certain psychiatric symptoms were associated with the level of suicide risk in the first episode of psychosis, such as «tension”,«hostility”,«mannerisms and posturing,«excitement»,«suspiciousness»,«somatic concern»,«anxiety»,«depression»,«guilt». Circadian rhythms include the level of risk occurrence and severity autoagressive behavior such as clearly and dimly expressed evening types of daily activity.

Conclusions: Therefore, further research of autoagression during the first psychotic episode with considering the influence of biological rhythms is a given area of current research in psychiatry aimed to improve the prevention, treatment and rehabilitation.