… of effective therapeutic approaches is impeded by lack of proper clinical biomarkers. In
this review, we summarized the current status and clinical relevance of biomarkers from …

… in clinical samples Protein phosphorylation plays a key role in many clinically relevant …
progression of diseases, discovering new biomarkers and evaluating treatment response in …

… these emerging modified biomarkers and mediators are increasingly gaining importance for
… Particularly clinically relevant is the progressive development in MALDI-imaging, permitting …

… to the identification of new biomarkers which are of relevant to clinical practice, enabling
researchers to use targeted therapeutic approaches in the treatment of cancer. Specific …

… important area in cancer research to understand cancer biology and discover novel biomarkers
and therapeutic … PTMs of high frequency with recognized importance in cancer biology, …

… been used to study fundamental and clinically relevant processes in cell culture or animal
… MALT1 is a paracaspase that plays an important role in regulating lymphocyte responses in …

… new diagnostic biomarkers and disease-modifying therapy and reduce these diseases’
burden. Specifically, post-translational modifications (PTMs) play a significant role … of biomarker …

… post-translational modification derived products (PTMDPs) have been suggested to be
promising biomarkers … evidences for the clinical relevance of PTMDPs as biomarkers in chronic …

… usefulness of novel advances in the class of biochemical markers, neo-epitopes. Neo-epitopes
are post-translational … It is not enough to develop good, well performing clinically relevant …

… Core tip: The purpose of the review is to describe the potential of histone … the role of histone
post-translational modifications and its utility in cancer diagnosis, prognosis and treatment. …