Clinical relevance of mortalin in ovarian cancer patients
Background: Ovarian cancer (OC) is the most lethal malignancy of the female reproductive
tract. Consequently, a better understanding of the malignant features in OC is pertinent.
Mortalin (mtHsp70/GRP75/PBP74/HSPA9/HSPA9B) promotes cancer development,
progression, metastasis, and recurrence. Yet, there is no parallel evaluation and clinical
relevance of mortalin in the peripheral and local tumor ecosystem in OC patients. Methods:
A cohort of 92 pretreatment women was recruited, including 50 OC patients, 14 patients with …
tract. Consequently, a better understanding of the malignant features in OC is pertinent.
Mortalin (mtHsp70/GRP75/PBP74/HSPA9/HSPA9B) promotes cancer development,
progression, metastasis, and recurrence. Yet, there is no parallel evaluation and clinical
relevance of mortalin in the peripheral and local tumor ecosystem in OC patients. Methods:
A cohort of 92 pretreatment women was recruited, including 50 OC patients, 14 patients with …
[PDF][PDF] Clinical Relevance of Mortalin in Ovarian Cancer Patients. Cells 2023, 12, 701
Background: Ovarian cancer (OC) is the most lethal malignancy of the female reproductive
tract. Consequently, a better understanding of the malignant features in OC is pertinent.
Mortalin (mtHsp70/GRP75/PBP74/HSPA9/HSPA9B) promotes cancer development,
progression, metastasis, and recurrence. Yet, there is no parallel evaluation and clinical
relevance of mortalin in the peripheral and local tumor ecosystem in OC patients. Methods:
A cohort of 92 pretreatment women was recruited, including 50 OC patients, 14 patients with …
tract. Consequently, a better understanding of the malignant features in OC is pertinent.
Mortalin (mtHsp70/GRP75/PBP74/HSPA9/HSPA9B) promotes cancer development,
progression, metastasis, and recurrence. Yet, there is no parallel evaluation and clinical
relevance of mortalin in the peripheral and local tumor ecosystem in OC patients. Methods:
A cohort of 92 pretreatment women was recruited, including 50 OC patients, 14 patients with …
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