Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase
BG Sánchez, A Bort, PA Mateos-Gómez… - Cancer Cell …, 2019 - Springer
Background Current chemotherapy for castration-resistant prostate cancer is established on
taxane-based compounds like docetaxel. However, eventually, the development of toxic
side effects and resistance limits the therapeutic benefit being the major concern in the
treatment of prostate cancer. Combination therapies in many cases, enhance drug efficacy
and delay the appearance of undesired effects, representing an important option for the
treatment of castration-resistant prostate cancer. In this study, we tested the efficacy of the …
taxane-based compounds like docetaxel. However, eventually, the development of toxic
side effects and resistance limits the therapeutic benefit being the major concern in the
treatment of prostate cancer. Combination therapies in many cases, enhance drug efficacy
and delay the appearance of undesired effects, representing an important option for the
treatment of castration-resistant prostate cancer. In this study, we tested the efficacy of the …
Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase
B Sánchez Gómez, AC Bort Bueno, PA Mateos Gómez… - 2019 - ebuah.uah.es
Background Current chemotherapy for castration-resistant prostate cancer is established on
taxane-based compounds like docetaxel. However, eventually, the development of toxic
side effects and resistance limits the therapeutic benefit being the major concern in the
treatment of prostate cancer. Combination therapies in many cases, enhance drug efficacy
and delay the appearance of undesired effects, representing an important option for the
treatment of castration-resistant prostate cancer. In this study, we tested the efficacy of the …
taxane-based compounds like docetaxel. However, eventually, the development of toxic
side effects and resistance limits the therapeutic benefit being the major concern in the
treatment of prostate cancer. Combination therapies in many cases, enhance drug efficacy
and delay the appearance of undesired effects, representing an important option for the
treatment of castration-resistant prostate cancer. In this study, we tested the efficacy of the …
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