Combined high-density lipoprotein proteomic and glycomic profiles in patients at risk for coronary artery disease
Objectives: To test whether recently developed methods for comprehensive profiling of the
high-density lipoprotein (HDL) glycome combined with the HDL proteome can distinguish
individuals with coronary artery disease (CAD) from those without. Methods: Twenty subjects
at risk for CAD, who underwent diagnostic coronary arteriography, were analyzed. Ten
subjects had CAD, and ten did not. HDL was extracted from fasting plasma samples by
ultracentrifugation, followed by shotgun proteomic, glycomic, and ganglioside analyses …
high-density lipoprotein (HDL) glycome combined with the HDL proteome can distinguish
individuals with coronary artery disease (CAD) from those without. Methods: Twenty subjects
at risk for CAD, who underwent diagnostic coronary arteriography, were analyzed. Ten
subjects had CAD, and ten did not. HDL was extracted from fasting plasma samples by
ultracentrifugation, followed by shotgun proteomic, glycomic, and ganglioside analyses …
[引用][C] Combined High-Density Lipoprotein Proteomic and Glycomic Profiles in Patients at Risk for Coronary Artery Disease
K Sridevi, H Jincui, L Hyeyoung, G Andres, B Lars… - 2015