The present study was conducted to proceed a comparison between efficiency of chemotherapy and alcoholic extract of plant leaves Melia azedarch L. in the growth of many fungi that cause Tinea capitis in humans using 24 samples belonging to patients with Tinea capitis of Kerion of the children ranged in age (1-18) years old and both sexes dermatophytosis who clinically diagnosed by dermatologist, from Al-Sadder Medical City in Al-Najaf Government, from January to November 2016, by using traditional methods for laboratory isolation and identification. The results shown indicated many fungus Microsporum canis and Microsporum gypseum and Trichophyton verrucosum. the biochemical test refer, M. canis featured its growth on the rice media and excellence fungus M. gypseum its growth at the corn flour with 80 Tween with Trypan blue The fungus T. verrucosum have a clear growth on 1, 2 Trichphyton Agar. on the other hands, results indicated in the M. canis is the predominant type and cause Tinea capitis within the studied samples as the incidence rate of 42% with this fungus, followed by M. gypseum in effect since the infection rate was 38%, and T. verrucosum was less influential as the incidence rate of 21%. Results showed the relationship between infection and age and sex, the males were more susceptible to infection than females especially in ages (12-7) years high infection. Moreover, in present study found a different concentration of alcoholic extract of leaves Melia azedarch L in inhibiting the growth of fungi especially for concentrations (60 and 80%). on the other hand, when using antibiotics in the treatment of skin infections and compared alcoholic extract leaves Melia azedarch L. result appear sensitivity of fungus to antibiotics as it reached the infection ratio (69.7, 40.9, 77.7)% of ketoconazole antifungal M. canis, T. verrucosum, M. gypsem respectively while fungi tested did not appear affected and clear for antibiotic Flouconazole compared with the rest of antibiotics as it was (10.2, 5.0, 11.5)% respectively.