[HTML][HTML] Comparison of clinical scoring systems in the management of patients with microangiopathic hemolytic anemia and thrombocytopenia
M Baysal, E Ümit, HO Kırkızlar… - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: Several clinical scoring systems have been developed for the differential
diagnosis of thrombotic microangiopathies (TMAs), all to predict and identify patients with
ADAMTS13 deficiency and to start treatment as soon as possible. The first scoring system in
this regard was the Bentley score, and the French score and PLASMIC score were
developed afterwards. Materials and Methods: We aimed to evaluate the laboratory
parameters and clinical features of patients who underwent plasma exchange with a …
diagnosis of thrombotic microangiopathies (TMAs), all to predict and identify patients with
ADAMTS13 deficiency and to start treatment as soon as possible. The first scoring system in
this regard was the Bentley score, and the French score and PLASMIC score were
developed afterwards. Materials and Methods: We aimed to evaluate the laboratory
parameters and clinical features of patients who underwent plasma exchange with a …
Abstract
Objective:
Several clinical scoring systems have been developed for the differential diagnosis of thrombotic microangiopathies (TMAs), all to predict and identify patients with ADAMTS13 deficiency and to start treatment as soon as possible. The first scoring system in this regard was the Bentley score, and the French score and PLASMIC score were developed afterwards.
Materials and Methods:
We aimed to evaluate the laboratory parameters and clinical features of patients who underwent plasma exchange with a prediagnosis of TTP at our clinic between 2007 and 2019 and whose ADAMTS13 enzyme levels were measured and to compare the findings with the scoring systems.
Results:
Data of 35 patients were evaluated. Twelve patients were evaluated as high risk according to all three scoring systems. A statistically significant relation was observed between all three scoring systems and ADAMTS13 levels.
Conclusion:
A moderate correlation was found between all three scoring systems and ADAMTS13 levels. We observed similar potential strength of all three scoring systems to predict TTP among other TMAs and we conclude that they are applicable in daily practice.
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