Comparison of the classically conditioned withdrawal reflex in cerebellar patients and healthy control subjects during stance: I. Electrophysiological characteristics

D Timmann, T Kaulich, W Foehre, DF Kutz, M Gerwig… - The Cerebellum, 2013 - Springer
The aim of this study was to demonstrate the involvement of the human cerebellum in the
classically conditioned lower limb withdrawal reflex in standing subjects. Electromyographic
activity was recorded from the main muscle groups of both legs of eight patients with
cerebellar disease (CBL) and eight control subjects (CTRL). The unconditioned stimulus
(US) consisted of electrical stimulation of the tibial nerve at the medial malleolus. The
conditioning stimulus (CS) was an auditory signal given via headphones. Experiments …

Comparison of the classically conditioned withdrawal reflex in cerebellar patients and healthy control subjects during stance: 2. Biomechanical characteristics

DF Kutz, T Kaulich, W Foehre, M Gerwig… - Neurobiology of learning …, 2014 - Elsevier
This study addresses cerebellar involvement in classically conditioned nociceptive lower
limb withdrawal reflexes in standing humans. A preceding study compared
electromyographic activities in leg muscles of eight patients with cerebellar disease (CBL)
and eight age-matched controls (CTRL). The present study extends and completes that
investigation by recording biomechanical signals from a strain-gauge-equipped platform
during paired auditory conditioning stimuli (CS) and unconditioned stimuli (US) trials and …
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