Background The urea breath test (UBT) is the gold-standard non-invasive test for the
detection of Helicobacter pylori infection, however, the lack of availability of the UBT due to
the high cost of the test, and in particular the need for expensive analytical instrumentation,
limits the usefulness of this method. Stool antigen assays may offer an alternative non-
invasive method for the diagnosis of infection. Objective To compare the accuracy of three
stool antigen assays (HpSA, IDEIA HpStAR, and ImmunoCard STAT) against the UBT for the …

Aim: To compare three stool antigen assays: Premier platinum HpSA (Meridan Diagnostics);
IDEIA-HpStAR (Daykocytomation); and the ImmunoCardSTAT (Meridian Diagnostics),
against the urea breath test, and to assess their acceptability as an alternative to the UBT for
the primary diagnosis of H. pylori infection and for monitoring treatment outcome. Methods:
102 dyspeptic patients provided breath and stool samples. Patients who tested positive for
H. pylori by the validated UBT test were prescribed triple therapy and asked to return for …