过去一年中添加的文章,按日期排序

Comparative analysis of single cell expression and digital spatial profiling in FFPE tumor tissues

A Moore, A O'Hara, P Vishwanath, L Turner, H Latif… - Cancer Research, 2024 - AACR
112 天前 - … Here we present a comparative analysis of two transcriptomic modalities within one
… of the transcriptome and digital spatial profiling of the whole transcriptome. Independent …

Revealing a Novel Methylated Integrin Alpha-8 Related to Extracellular Matrix and Anoikis Resistance Using Proteomic Analysis in the Immune Microenvironment of …

T Liu, W Ji, X Cheng, L Lv, X Yu, N Wang, M Li… - Molecular …, 2024 - Springer
112 天前 - transcriptome data, miRNAs expression data, and clinical patient information for
LUAD based on The CancerComprehensive analyses of ITGA8 revealed it combined focal …

An integrative pan-cancer analysis of the molecular characteristics of dietary restriction in tumour microenvironment

X Song, J Wei, Y Li, W Zhu, Z Cai, K Li, J Wei, J Lu… - Ebiomedicine, 2024 - thelancet.com
115 天前 - overall survival (OS) and cancer-specific survival (CSS). In summary, our integrated
analyses … DR-related molecular activities in the tumour microenvironment, shedding light on …

LEVERAGING DIGITAL SPATIAL PROFILING TO IDENTIFY TRANSCRIPTIONAL SIGNATURES ASSOCIATED WITH UROTHELIAL CARCINOMA IN SITU

N Frydenlund, JJ Meeks, X Lu, B Choy, R Yang… - … Oncology: Seminars and …, 2024 - Elsevier
133 天前 - … to normalnormal urothelium to CIS. As proof of concept, using the nanoString
GeoMx DSP platform we performed whole transcriptome analysis of CIS specimens and normal

Development of a necroptosis-related prognostic model for uterine corpus endometrial carcinoma

Q Zhang, Y Luo, S Zhang, Q Huang, G Liu - Scientific Reports, 2024 - nature.com
142 天前 - … functional analysis was conducted to explore the potential mechanisms of these
target genes. Subsequently, immune infiltration analysis was performed using transcriptome

Comprehensive analysis of m6A methylome and transcriptome by Nanopore sequencing in clear cell renal carcinoma

H Li, C Li, Y Zhang, W Jiang, F Zhang… - Molecular …, 2024 - Wiley Online Library
147 天前 - … In conclusion, this study investigated the differential m 6 A methylome and
transcriptome profiles between ccRCC tumor and tumor-adjacent normal tissues, revealing the …

Abstract A076: The role of PARP-1-mediated FoxA1 ADP-ribosylation in breast cancer biology

CV Camacho, A Sundaresan, T Nandu, WL Kraus - Cancer Research, 2024 - AACR
162 天前 - cancer cell transcriptome. Indeed, the sites of FoxA1 ADPRylation are recurrently
mutated in breast cancers and are highly enriched in metastatic cases. Using an integrated …

Abstract B033: Mapping subclonal epigenetic evolution in colorectal cancer by spatial analysis of DNA hypermethylation

NJ Spix, H Milliron, M Kalkat, E Eugster, DW Chesla… - Cancer Research, 2024 - AACR
162 天前 - … Remaining tumor tissue is preserved in the form of spatially annotated FFPE blocks,
… used for analyses such as high-plex immunofluorescence or spatial transcriptomics. Using …

Abstract B002: Profiling intra-tumor heterogeneity and chromosomal instability in malignant peripheral nerve sheath tumors

Y Cheng, H Yan, M Tarabichi, Z Zhang, C Gao… - Cancer Research, 2024 - AACR
162 天前 - tumor phylogenetic trees. Intriguingly, our findings indicate that for patient 2.3, primary
tumor samples PT_1 and PT_2 displayed a close … , we leveraged normal cells identified …

Abstract PR014: Multiregion biopsies and corresponding neurosphere cultures reveal spatial divergence in glioblastoma evolution

R Salatino, U Onubogu, B Oakes, O Szentirmai… - Cancer Research, 2024 - AACR
162 天前 - cancer cells (predominantly 5-ALA high ) from tumor microenvironment (5-ALA low
) and subjected the fractions to bulk and single cell transcriptomics… location in the tumor, with …