[HTML][HTML] Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients

LSF Boogerd, MC Boonstra, AJ Beck, A Charehbili… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Folate receptor alpha (FRα) is known to be upregulated in a variety of cancers, including
non-small cell lung cancer (NSCLC) and breast cancer. To ensure reliable implementation
of diagnostic-and therapeutic agents, concordance of FRα expression between biopsy,
primary tumor and metastases is important. Using immunohistochemistry (Mab 26B3. F2)
these concordances were investigated in 60 NSCLC and 40 breast cancer patients. False
positivity of FRα expression on breast and lung cancer biopsies was limited to less than 5 …

[引用][C] Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients. Oncotarget. 2016; 7 (14) …

L Boogerd, M Boonstra, A Beck, A Charehbili… - Drug design, development …, 2015
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