Confounders for prognostic accuracy of neuron-specific enolase after cardiac arrest: A retrospective cohort study
C Czimmeck, M Kenda, N Aalberts, C Endisch… - Resuscitation, 2023 - Elsevier
Aim To evaluate neuron-specific enolase (NSE) thresholds for prediction of neurological
outcome after cardiac arrest and to analyze the influence of hemolysis and confounders.
Methods Retrospective analysis from a cardiac arrest registry. Determination of NSE serum
concentration and hemolysis-index (h-index) 48–96 hours after cardiac arrest. Evaluation of
neurological outcome using the Cerebral Performance Category score (CPC) at hospital
discharge. Separate analyses considering CPC 1–3 and CPC 1–2 as good neurological …
outcome after cardiac arrest and to analyze the influence of hemolysis and confounders.
Methods Retrospective analysis from a cardiac arrest registry. Determination of NSE serum
concentration and hemolysis-index (h-index) 48–96 hours after cardiac arrest. Evaluation of
neurological outcome using the Cerebral Performance Category score (CPC) at hospital
discharge. Separate analyses considering CPC 1–3 and CPC 1–2 as good neurological …
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