Batch and semibatch reactors are the main device of batch processes which are still widely
used to produce pharmaceuticals, polymers, biotechnologicals etc. Fine chemical
transformations are characterized by quite complex reaction systems which can produce
undesirable end products. As the aim of the fine chemical industry is to produce high quality
and purity products, it is essential to optimize batch operating conditions, ie temperature
profile, feed flow rate, amount of reactant and final batch time, taking into account constraints …