Environmentally responsive materials are attractive for advance biomedicine applications
such as controlled drug delivery and gene therapies. Recently, we have introduced the
fabrication of a novel type of stimuli-sensitive lipogel composite consisting of poly (N-
isopropylacrylamide)(pNIPAM) microgel particles and lipids. In this study, we demonstrated
the temperature-triggered drug release behavior and the tunable drug loading and release
capacities of the lipogel. At room temperature (22° C), no calcein was released from the …