Conversion of Glycerol to 3-Hydroxypropanoic Acid by Genetically Engineered Bacillus subtilis
3-Hydroxypropanoic acid (3-HP) is an important biomass-derivable platform chemical that
can be converted into a number of industrially relevant compounds. There have been
several attempts to produce 3-HP from renewable sources in cell factories, focusing mainly
on Escherichia coli, Klebsiella pneumoniae, and Saccharomyces cerevisiae. Despite the
significant progress made in this field, commercially exploitable large-scale production of 3-
HP in microbial strains has still not been achieved. In this study, we investigated the …
can be converted into a number of industrially relevant compounds. There have been
several attempts to produce 3-HP from renewable sources in cell factories, focusing mainly
on Escherichia coli, Klebsiella pneumoniae, and Saccharomyces cerevisiae. Despite the
significant progress made in this field, commercially exploitable large-scale production of 3-
HP in microbial strains has still not been achieved. In this study, we investigated the …
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