Coordinated microRNA and messenger RNA expression profiles for understanding sexual dimorphism of gonads and the potential roles of microRNA in the …

W Wang, W Liu, Q Liu, B Li, L An, R Hao, J Zhao, S Liu… - Theriogenology, 2016 - Elsevier
Sexual dimorphism is a widespread phenomenon in animals. However, the potential role of
microRNAs (miRNAs) in regulating this dimorphism is not fully understood. In our study, we
used an integrated approach to identify functional targets of miRNA by combining the paired
expression profiles of miRNAs and messenger RNAs (mRNAs) in ovaries and testes of
young Nile tilapia, Oreochromis niloticus. The results revealed that 67 upregulated and nine
downregulated miRNAs and 2299 upregulated and 3260 downregulated genes were …

Coordinated microRNA and messenger RNA expression profiles for understanding sexual dimorphism of gonads and the potential roles of microRNA in the …

WWW Wang WeiWei, LWZ Liu WenZhong, LQ Liu Qing… - 2016 - cabidigitallibrary.org
Sexual dimorphism is a widespread phenomenon in animals. However, the potential role of
microRNAs (miRNAs) in regulating this dimorphism is not fully understood. In our study, we
used an integrated approach to identify functional targets of miRNA by combining the paired
expression profiles of miRNAs and messenger RNAs (mRNAs) in ovaries and testes of
young Nile tilapia, Oreochromis niloticus. The results revealed that 67 upregulated and nine
downregulated miRNAs and 2299 upregulated and 3260 downregulated genes were …
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