Corneal neurotization: review of a new surgical approach and its developments

N Wolkow, LA Habib, MK Yoon… - Seminars in …, 2019 - Taylor & Francis
Seminars in Ophthalmology, 2019Taylor & Francis
Background: Corneal neurotization is an innovative surgical approach for restoring corneal
sensation, whereby the sensory functions of a normal donor nerve are rerouted to an
anesthetic cornea. Many variations upon this basic surgical principal have been introduced
and have proven successful in ameliorating corneal sensation in patients. It is unclear
whether one surgical approach is superior to another, as each has advantages and
disadvantages. Surgical approaches differ in the donor nerve selected and in whether a …
Background
Corneal neurotization is an innovative surgical approach for restoring corneal sensation, whereby the sensory functions of a normal donor nerve are rerouted to an anesthetic cornea. Many variations upon this basic surgical principal have been introduced and have proven successful in ameliorating corneal sensation in patients. It is unclear whether one surgical approach is superior to another, as each has advantages and disadvantages. Surgical approaches differ in the donor nerve selected and in whether a nerve graft is required. Surgical techniques have varied in the location, number and extent of incisions, methods of nerve coaptation, the number of surgeons required, the equipment and materials utilized and the duration of the procedure.
Purpose
The current review provides an overview of developments in this nascent field.
Methods
A review of all peer-reviewed publications on corneal neurotization was performed. The various approaches to corneal neurotization are compared and discussed.
Conclusions
The least morbid, simplest, most expedient and successful surgical approaches will ultimately become the most utilized.
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