Cox11p is required for stable formation of the CuBand magnesium centers of cytochrome c oxidase

L Hiser, M Di Valentin, AG Hamer, JP Hosler - Journal of Biological …, 2000 - ASBMB
Assembly of the core subunits of theaa 3-type cytochrome c oxidase in mitochondria and
aerobic bacteria such as Rhodobacter sphaeroides requires the association of three
subunits and the formation of five to seven metal centers. Several assembly proteins are
required for the late stages of oxidase assembly in eukaryotes; some of these are also
present in Rb. sphaeroides. To investigate the role of one of these proteins, Cox11p, the
mitochondrial-like oxidase of Rb. sphaeroides was overexpressed and purified from cells …
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