Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome

JP Goncalves, A Oliveira, M Severo, AC Santos… - Endocrine, 2012 - Springer
Research on the importance of serum uric acid (SUA) as a contributing metabolic factor to
cardiovascular diseases has conducted to conflicting results, with most studies assuming a
cross-sectional design. The aim of this study was to evaluate the association of SUA and
metabolic syndrome (MetS) and its features. A representative sample of 2,485 individuals
aged≥ 18 years was randomly selected from the non-institutionalized resident population of
Porto, Portugal. A total of 1,054 eligible subjects were included for the longitudinal analyses …

Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome: Results from Fangchenggang Area Male Health and Examination …

D Chen, H Zhang, Y Gao, Z Lu, Z Yao, Y Jiang, X Lin… - Clinica Chimica …, 2015 - Elsevier
Background It is controversial whether serum uric acid (SUA) is a risk factor for the
prevalence of metabolic syndrome (MetS). The current study was designed to highlight the
association of SUA and MetS and its components. Methods Data on 3675 healthy male
subjects, aged 17–88 years, were collected for the cross-sectional study. A representative
sample of 2575 individuals who did not suffer from MetS at baseline was involved in the
cohort study. A cox regression model was applied to evaluate causality for the 2-and 4-year …
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