Evaluation of clopidogrel response variability and identification of the CYP2C19 polymorphism in Mexican patients

ME Viveros, C Areán, S Gutiérrez… - … de cardiología de …, 2016 - scielo.org.mx
… of these studies investigated clopidogrel response. The absence of the polymorphism in the
present … that the inter-individual response to clopidogrel must be influenced by other factors. …

Proton pump inhibitors, genetic polymorphisms and response to clopidogrel therapy

H Fernando, AM Dart, K Peter… - Thrombosis and …, 2011 - thieme-connect.com
… followed by assessment of the impact of PPIs and polymorphisms on clopidogrel’s efficacy
with … Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360: …

Evaluation of CYP2C19, P2Y12, and ABCB1 polymorphisms and phenotypic response to clopidogrel in healthy Indian adults

K Sridharan, R Kataria, D Tolani… - Indian Journal of …, 2016 - journals.lww.com
… [ 6 ] Considering the paucity of Indian data regarding the influence of CYP2C19, P2Y12,
and ABCB1 genetic polymorphisms on the antiplatelet effect of clopidogrel, we conducted this …

[PDF][PDF] Genotyping of six clopidogrel-metabolizing enzyme polymorphisms has a minor role in the assessment of platelet reactivity in patients with acute coronary …

MH García-Lagunar… - Anatolian Journal of …, 2017 - jag.journalagent.com
… the variability in response to clopidogrel explained by the six polymorphisms is poor when
Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360: …

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response

RP Kreutz, P Nystrom, Y Kreutz, J Miao… - Clinical …, 2012 - Taylor & Francis
… platelet inhibition by clopidogrel and high on-treatment platelet aggregation. PON1 (Q192R)
polymorphism does not appear to be a significant determinant of clopidogrel response. …

Pharmacogenetic study of CYP2C19 variation and clopidogrel dose adjustment according to platelet reactivity monitoring in atherothromboticrisk patients in Thailand

R Tunthong, C Sukasem, A Puangpetch… - Current …, 2013 - ingentaconnect.com
… impact of CYP2C19 polymorphisms on platelet response after clopidogrel dose adjustment.
Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360(4): …

The genetic basis of platelet responsiveness to clopidogrel

P Fefer, S Matetzky - Thrombosis and haemostasis, 2011 - thieme-connect.com
… in clopidogrel-induced platelet inhibition, and a substantial proportion of patients will exhibit
non-responsiveness to clopidogrel. … polymorphisms associated with suboptimal clopidogrel-…

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with …

C Varenhorst, S James, D Erlinge… - European heart …, 2009 - academic.oup.com
… Although polymorphisms of the P2Y 12 receptor have been … clopidogrel response in patients
with CAD. In addition, as the P2Y 12 receptor is the target for both prasugrel and clopidogrel

Nonresponders to clopidogrel: pharmacokinetics and interactions involved

MA Giorgi, G Di Girolamo… - Expert opinion on …, 2010 - Taylor & Francis
… evidence supports some CYP2C19 polymorphisms on clopidogrel efficacy and effectiveness…
6 – 12 h from the administration of clopidogrel to evaluate its response. However, in patients …

[HTML][HTML] Effect of cytochrome P450 2C19 (CYP2C19) gene polymorphism and clopidogrel reactivity on long term prognosis of patients with coronary heart disease …

HU Cheng-Yan, W Yan-Ling… - Journal of Geriatric …, 2024 - ncbi.nlm.nih.gov
… low response to clopidogrel in patients with coronary heart disease is correlated with CYP2C19
gene polymorphism, … in patients undergoing stenting with clopidogrel treatment, which is …