… evidence supports some CYP2C19 polymorphisms on clopidogrel efficacy and effectiveness…
6 – 12 h from the administration of clopidogrel to evaluate its response. However, in patients …

… study participated in a larger study conducted by the same organization to examine the
effects of genetic polymorphisms involved in clopidogrel metabolism in NSTE ACS patients [ …

… intermediate or poor metabolisers of clopidogrel. Rest of the … CYP2C19 haplotypes and
clopidogrel antiplatelet response, the … CYP2C19*2 polymorphic allele and clopidogrel resistance. …

… improved antiplatelet activity of clopidogrel therapy in carriers … polymorphisms of CYP2C19
on the response to clopidogrel has … genetic polymorphisms on the response to clopidogrel in …

… nucleotide polymorphisms (SNPs) with regard to clopidogrel … and *17 variants on clopidogrel
response are independent of … To test this, we evaluated the effects of these polymorphisms …

… polymorphisms account for only approximately 12% of variability in clopidogrel platelet
response; 3) the positive predictive value of CYP2C19 loss-of-function polymorphisms for …

… Clopidogrel is an antiplatelet prodrug primarily … (IS), polymorphisms of genes encoding
cytochrome P-450 (CYP) and P-glycoprotein transporter, could affect the efficiency of clopidogrel …

… genetic polymorphism in the clinical response to clopidogrel. … effect of the CYP3A5 genetic
polymorphism, since most of the … Genetic polymorphisms of CYP2C19 modulate clopidogrel …

… response. It is also equally … clopidogrel responses in Asian populations, we will briefly
discuss the mechanism of action of clopidogrel, the mechanism of variable clopidogrel response, …

… In this review, we focus mainly on outlining the genetic polymorphisms associated with
the variability in antiplatelet response to clopidogrel and the difference in clinical outcomes …