… and in patients who have been treated with corticosteroids, … -inflammatory cytokine that is
upregulated in pulmonary fibrosis. … These animal models suggest that modulating fibrocyte …

… in dependency to the cytokine milieu. IL-12 and IFN-γ polarize lymphocytes toward the Th1
… potential of this drug to modulate the innate immune response in patients with CHP is worth …

… immunosuppression. Also, preliminary data suggest that disease severity in COVID-19 may
be associated with low IFN-γ … IL-6 levels are detrimental-why shouldn't corticosteroids be first …

… Immunosuppressive therapy fails to suppress the production … all subjects produced IFN-γ/TNF-α
proinflammatory cytokines. … /ml cyclosporin A and 1 µM prednisolone inhibit IFN-γ/TNF-α …

… of prototypic T H 1 (IFN-γ and IL-12), T H 2 (IL-4 and IL-5), and regulatory (TGF-β) cytokines,
and … T H 2/T H 1 cytokine balance and modulating CD8 suppressor activity. Although the …

… , treatment with interferon gamma (IFN‐γ), a type‐1 T‐helper cell (Th1)‐derived cytokine, … )
a present or past history of treatment with glucocorticoid or immunosuppressive agents; 3) end …

… the adoption of immunosuppressive agents, commonly used … levels of pro-inflammatory
cytokines (IFN-γ, IL-1, IL-6) and … , corticosteroids, and TNF-α antagonists alone or in combined …

… inflammation as the profibrotic cytokine cascade is triggered … We previously showed that
IFN-γ and IL-4 had opposite … status, whereas GSH conversely modulates the Th1/Th2 balance(…

… cytokines, including tumor necrosis factor (TNF)-α, and IFN-γ … , azathioprine or mycophenolate
mofetil, and steroids. … panel of immune-modulating mediators in the plasma of human lung …

… binds to Smad-binding elements to modulate TGF-β target gene … Also, IFN-γ treatment in the
early stage of viral infection may … IL-4, IL-6 and IL-17 also contribute to pulmonary fibrosis by …