… been made in understanding cells, cytokines, receptors, and matrix … ; 29 initially were treated
with corticosteroids with or without … Limitations of traditional immunosuppressive therapy …

… pleiotropic effects, neither is immunosuppressive per se, and … to IPF, despite traditional
treatments (eg, corticosteroids and … IFN-γ and CXCL10 concentrations are raised in patients with …

… , such as corticosteroids, cytotoxic drugs, and IFN-γ, have been … one of the key cytokines
involved in pulmonary fibrosis (12). … that cav-1 might modulate smad activity. The effect of cav-…

… shown to modulate the transcription of procollagen 1 and 3 (… In animal models of pulmonary
fibrosis IFN-γ production has … Corticosteroids exert broad transcriptional changes in both …

… In SARC but not in IPF, IFN-γ mRNA was expressed at high levels … enzymes and cytokines
plays a major role in the modulation of the … Two patients received a steroid therapy with 40 mg …

… , even though IFN-γ appears to be the most critical cytokine in … The successful modulation
of MAC levels in blood by IFN-γ … IFN-γ allowed rapid reduction in steroid dose and led to cure …

… , such as corticosteroids and some immunosuppressants, … prednisolone) inhibited the
elevation of profibrotic cytokines, … deterioration of interferon gamma (IFN-γ) to maintain Th1/Th2 …

… they were on systemic corticosteroid therapy. None of the … the idiopathic ERM group, vitreous
levels of IL-6, IL-10, IFN-γ, … , and/or injured tissue cells modulates inflammatory process by …

… effective as an immunosuppressant drug. It is used to … were detected in our results including
the cytokines IFN-γ, IL-4, IL-5, … -fve and corticosteroid treatment on the Th1 (IL-12 and IFN-γ) …

… previous findings for IFN-γ production by CD8 + … modulation of granzyme B in T, NK, and
NKT-like cells in the presence of therapeutic doses of cyclosporine, tacrolimus, or prednisolone, …