Cryptogenic fibrosing alveolitis/idiopathic pulmonary fibrosis

RM Du Bois, AU Wells - European Respiratory Journal, 2001 - Eur Respiratory Soc
… , interleukin (IL)‐1 and IL6; chemokines known to enhance the … options for potential future
therapy for IPF are IFNγ, anti-TNF… , indirect evidence that treatment can modulate the natural …

Adverse effects of immunosuppressant drugs upon airway epithelial cell and mucociliary clearance: implications for lung transplant recipients

R Pazetti, PM Pêgo-Fernandes, FB Jatene - Drugs, 2013 - Springer
cytokines. This review focuses the current armamentarium of … infiltration and spot frequencies
for IFN-γ. However, only oral … whether tacrolimus was able to modulate PGE2 production in …

Macrolide antibiotics as immunomodulatory medications: proposed mechanisms of action

M Shinkai, MO Henke, BK Rubin - Pharmacology & therapeutics, 2008 - Elsevier
… antibiotics in the treatment of steroid dependent asthma. Many … initially increases
proinflammatory cytokine secretion via … macrolide-induced cytokine secretion modulation. This …

Anti-inflammatory medications for cystic fibrosis lung disease: selecting the most appropriate agent

JF Chmiel, MW Konstan - Treatments in respiratory medicine, 2005 - Springer
… Studies of molecules that modulate intracellular signaling … that was associated with
decreased serum IgG and cytokine … 1000μg but not 500μg of inhaled IFN-γ had a statistically …

Anti-inflammatory and immunomodulatory properties of azithromycin involved in treatment and prevention of chronic lung allograft rejection

R Vos, BM Vanaudenaerde, SE Verleden… - …, 2012 - journals.lww.com
… and expression of proinflammatory cytokines by inhibition of … necrosis factor-α and IFN-γ
expression and fibrous obliteration … Indeed, we recently provided further evidence for modulation

[HTML][HTML] Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development

E Jeong, H Hong, YA Lee, KS Kim - International Journal of Molecular …, 2024 - mdpi.com
… However, immunosuppression is the standard of care for patients … of inflammatory cytokines,
such as TNF-α, IL-6, and IFN-γ, … also observed with steroid treatments for fibrotic RA-ILD with …

Therapeutics for the management of cytokine release syndrome in COVID-19

S Ghosh, S Durgvanshi, SS Han… - Current topics in …, 2023 - ingentaconnect.com
… Only corticosteroid therapy has shown benefit so far, albeit … by modulating an endoplasmic
reticulum protein (sigma-1 … of cytokines and chemokines like TNF-α, IFN-α, IFNβ, IFN-γ, IL-…

[HTML][HTML] Pulmonary macrophages: a new therapeutic pathway in fibrosing lung disease?

AJ Byrne, TM Maher, CM Lloyd - Trends in molecular medicine, 2016 - cell.com
pulmonary fibrosis fails to respond to corticosteroid therapycorticosteroids in combination
with the immunosuppressive drug … of fibrosis because the function and cytokine repertoire of …

Inflammation and angiogenesis in fibrotic lung disease

MP Keane, RM Strieter, JP Lynch… - … and critical care …, 2006 - thieme-connect.com
… some level of unresponsiveness to corticosteroids.[32] … to the type 1 cytokine IFN-γ, IL-4
is a major type 2 cytokine that … -1 synthesis by murine lung fibroblasts modulates CD4 + T …

[PDF][PDF] The Th1 chemokine IP-10 in Systemic sclerosis

A Corrado - Clin. Ter, 2014 - clinicaterapeutica.it
… releasing IL-6, IP-10, and MCP-1 under the influence of IFN-γ … immunoglobulin versus
corticosteroid in treatment of Graves’ … Variable modulation by cytokines and thiazolidinediones of …