14 天前 - … Objective SLE is a chronic inflammatory autoimmune … complexes and proinflammatory
cytokines. Repository … insights into the therapeutic role of RCI in refractory SLE, as …

20 天前 - The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that
regulates innate immune responses by activating caspase-1 and the inflammatory cytokines …

22 天前 - Background/Purpose Age-associated B cells (ABCs) accumulate and contribute to
the pathogenesis of systemic autoimmune diseases like lupus. Despite recent insights into …

27 天前 - … that individuals with SLE have dysregulated levels of these cytokines compared to
the healthy … in the levels of these cytokines was observed in both SLE patients and SLE mice. …

37 天前 - … The gut microbiome has become a viable therapeutic target for both infectious
and … inflammasome along with increased inflammatory cytokine levels. Moreover, probiotic …

49 天前 - … targets in SLE and lupus nephritis, with two new medications receiving FDA approval
in the last 3 years. Herein we provide an overview of targeted therapies for SLE … cytokines. …

51 天前 - … arthritis, systemic lupus erythematosus (SLE) and cytokines. … Although no specific
cytokine driver was identified as the … therapeutic targets for mitigating cardiovascular risk. …

52 天前 - … ; and secretion of proinflammatory cytokines from T cells patients with SLE. Taken
together … of dimethyl fumarate, with a distinct mechanism of action, as a novel therapy for SLE. …

53 天前 - … Macrophage Migration Inhibitory Factor (MIF) is a pleotropic pro-inflammatory cytokine
… sclerosis, rheumatoid arthritis, and systemic lupus erythematous. Given the association …

58 天前 - … Cytokine Release To further characterize the in vitro functionality of SLE CAR T
cells, we measured secreted cytokine levels after 16 hours. Co-culture of CAR T cells with …