DEEP2: Deep Learning Powered De-scattering with Excitation Patterning

N Wijethilake, DN Wadduwage - Microscopy Histopathology and …, 2022 - opg.optica.org
… Abstract: We present DEEP2, a computational multiphoton microscope to image through
scattering tissue. In … To address this limitation we previously introduced DEEP (de-scattering
with excitation patterning) [1]. Here we extend our work to DEEP2, that uses: (1) original
DEEP’s temporally focused pattered excitations to spatially encode image information
before emission light scattering and (2) a new Deep learning inverse solver to reconstruct
clean images from scattered measurements. …

DEEP2: Deep learning powered de-scattering with excitation patterning (DEEP)

N Wijethilake, M Anandakumar, C Zheng, PTC So… - 2023 - dspace.mit.edu
Graded index (GRIN) lens endoscopy has broadly benefited biomedical microscopic
imaging by enabling accessibility to sites not reachable by traditional benchtop
microscopes. It is a long-held notion that GRIN lenses can only be used as rigid probes,
which may limit their potential for certain applications. Here, we describe bendable and long-
range GRIN microimaging probes for a variety of potential micro-endoscopic biomedical
applications. Using a two-photon fluorescence imaging system, we have experimentally …
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