DMSO supplementation during in vitro maturation of bovine oocytes improves blastocyst rate and quality
AE Ynsaurralde-Rivolta, M Suvá, CG Luchetti… - Theriogenology, 2020 - Elsevier
The molecule Dimethyl sulfoxide is widely used as drug solvent. However, its antioxidant
property was poorly explored. In this study, we evaluated the effect of DMSO
supplementation during oocyte in vitro maturation (IVM) on embryo development and
quality. Bovine oocytes were matured with different DMSO concentrations (0, 0.1, 0.25, 0.5,
0.75, 1 and 10% v: v) followed by in vitro fertilization. Subsequently, quality indicators such
as gene expression of SOX2, OCT4, CDX2, SOD1, oocyte and embryo redox status and …
property was poorly explored. In this study, we evaluated the effect of DMSO
supplementation during oocyte in vitro maturation (IVM) on embryo development and
quality. Bovine oocytes were matured with different DMSO concentrations (0, 0.1, 0.25, 0.5,
0.75, 1 and 10% v: v) followed by in vitro fertilization. Subsequently, quality indicators such
as gene expression of SOX2, OCT4, CDX2, SOD1, oocyte and embryo redox status and …
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