过去一年中添加的文章,按日期排序

Multi-adductomics: Advancing mass spectrometry techniques for comprehensive exposome characterization

MR Chao, YJ Chang, MS Cooke, CW Hu - TrAC Trends in Analytical …, 2024 - Elsevier
2 天前 - … In DNA adductomics, a fundamental feature common to 2'-deoxyribonucleosides
(2'-dN) is a deoxyribose moiety connected to a nucleobase through a glycosidic bond. During …

An Integrated LC-MS/MS Platform for Noninvasive Urinary Nucleus Acid Adductomics: A Pilot Study for Tobacco Exposure

X Li, H Zeng, L Zhang, J Zhang, Y Guo… - Journal of Hazardous …, 2024 - Elsevier
68 天前 - … To evaluate all aspects of nucleic acid (NA) modifications, NA adductomics
analyzes DNA, RNA and nucleobase adducts and provides comprehensive data. Liquid …

Investigating the discriminatory potential of urinary DNA adductomics in smokeless tobacco-treated rats and head-neck cancer patients

SB Jorvekar, S Chouhan, G Narkhede, A Rai, A Das… - Microchemical …, 2024 - Elsevier
91 天前 - … (LC-MS/MS)-based DNA adductomics profiling has not been performed on
smokeless tobacco. Therefore, we performed DNA adductomics in this study through neutral loss …

DNA Modifications: Biomarkers for the Exposome?

C Möller, J Virzi, YJ Chang, A Keidel, MR Chao… - Environmental …, 2024 - Elsevier
113 天前 - … or a few DNA modifications at a time, limiting the information available. With the
development of DNA adductomics, which aims to determine the totality of DNA modifications, a …

DNA adductomics aided rapid screening of genotoxic impurities using nucleosides and 3D bioprinted human liver organoids

Y Li, C Xu, X Zhou, J Li, S Xu, Y Tu, X Mu, J Huang… - Talanta, 2024 - Elsevier
145 天前 - DNA adducts with carcinogenicity [6,8,9]. This study introduces a novel approach to
DNA adductomics studies: the reverse deduction of PGIs by analysing the structure of DNA

Mass Spectral Library for DNA Adductomics

SJ Walmsley, J Guo, A Tarifa… - Chemical research in …, 2024 - ACS Publications
203 天前 - … as a central location for the DNA adduct mass spectra and metadata, … DNA
adductomics community, accelerating research and improving our understanding of the role of DNA

From single DNA adducts measurement to DNA adductomics in molecular epidemiology of cancer

W Baer-Dubowska, H Szaefer - Postępy …, 2024 - postepybiochemii.ptbioch.edu.pl
210 天前 - … of DNA, screening for all DNA adducts, and … a DNA adductomics approach [8,9].
This paper presents the historical perspectives and new data on DNA adducts and adductomics

Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics

N Ragi, SJ Walmsley, FC Jacobs… - Chemical research in …, 2024 - ACS Publications
211 天前 - DNA adducts in human gastric mucosa. (96) Our laboratory extended the field of
DNA adductomics … and complete spectral characterization of the DNA adducts. (35) The CNL/…

A Novel Adductomics Workflow Incorporating FeatureHunter Software: Rapid Detection of Nucleic Acid Modifications for Studying the Exposome

CW Hu, YJ Chang, WH Chang, MS Cooke… - Environmental …, 2023 - ACS Publications
223 天前 - … of DNA modifications (ie, DNA adductomics (23,24)). Several DNA adductomics
(25,26) For DNA adductomics analysis using LC-HR-MS/MS, DNA adducts are featured …

[PDF][PDF] DNA adductomics: Toward applications in biological effect assessment and environmental monitoring

HV Motwani, E Gorokhova - Authorea Preprints, 2023 - essopenarchive.org
240 天前 - … Incorporating DNA adductomics into the existing biomarker … The DNA adductomics
workflow described here demonstrates that technology is ready for the integration of DNA