过去一年中添加的文章,按日期排序

Whole Genome Sequencing and single-cell transcriptomics identify KMT2D as a potential new driver for pituitary adenomas

M Brunner, J Meylan-Merlini, M Muriset, S Oreshkov… - medRxiv, 2024 - medrxiv.org
2 天前 - epigenetic landscape of pituitary tumors, we conducted a genome-wide DNA methylation
… This suggests that the interplay between genetic mutations, epigenetic regulation, and …

High Glucose Induces DNA methyltransferase 1 Dependent Epigenetic Reprogramming of the Endothelial Exosome Proteome in Type 2 Diabetes

S Vasishta, S Ammankallu, G Poojary… - … International Journal of …, 2024 - Elsevier
2 天前 - … Our study aimed to understand the DNA methylation-based epigenetic regulation
of the endothelial exosome proteome in the context of T2D. To our knowledge, this is the first …

Functional analyses of TET2 in vivo and in vitro reveal endothelial-specific roles in interferon responses that are dysregulated in hyperglycaemia

HLH Green, H Sum, P Sinha, A Visnagri, AC Brewer - 2024 - researchsquare.com
3 天前 - Epigenetic modi cations, most notably DNA methylation, … altered patterns of DNA
methylation and endothelial dysfunction … of the importance of epigenetic regulation by TET2 on …

DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life

D Martino, N Kresoje, N Amenyogbe… - Nature …, 2024 - nature.com
3 天前 - Epigenetic regulation is crucial in hematopoiesis and … that epigenetic modifications,
particularly DNA methylation, … whether dynamic changes in DNA methylation patterns are …

Non-coding regulation of transcription during plant development

BJM Tremblay - tdx.cat
4 天前 - epigenetic mechanisms such as non-coding RNAs, chromatin accessibility, DNA
methylation, and histone methylation… in regulating protein coding gene expression. To further …

On correlative and causal links of replicative epimutations

W Zhou, Y Reizel - Trends in Genetics, 2024 - cell.com
4 天前 - … transmission of DNA methylation, emphasizing the awareness of mitotic aging in …
DNA methylation dynamics in development and disease. We reviewed how DNA methylation

Investigating the Role of Environmental Exposures and piRNA Expression in Breast Cancer Initiation and Progression

K Polemi - 2024 - deepblue.lib.umich.edu
8 天前 - … and epigenetic mechanisms regulate cellular plasticity and breast carcinogenesis.
Epigenetic mechanisms such as DNA methylation … include genetic and epigenetic regulation, …

Deciphering regulation of FOXP3 in human primary CD4+ T cells

JM Umhoefer - 2024 - escholarship.org
9 天前 - … for proper expression of FOXP3 in Tconvs, including GATA3, STAT5, IRF4, ETS1
and DNA methylation-associated regulators DNMT1 and MBD2, a subset of which controls

The role of DNA methylation in facilitating life history trait diversity in fishes

J Kho, DE Ruzzante - Reviews in Fish Biology and Fisheries, 2024 - Springer
10 天前 - methylation throughout early development generally corresponds to elevated gene
expression … Finally, we discuss general limitations of DNA methylation studies with a focus …

Molecular biology and epigenetic modifications definition

F Khatami, RA Bahri, H Sharifkazemi, SM Sajadi… - … and Epigenetics of …, 2025 - Elsevier
14 天前 - … include DNA methylation and histone modifications, each altering gene expression
… Considering the importance of epigenetic regulation in cancers, epigenetic therapy has …