The role of DNA methylation in cancer

PA Jones, JD Buckley - Advances in cancer research, 1990 - Elsevier
Publisher Summary This chapter discusses the role of DNA methylation in carcinogenesis
and tumor diversification. The methylation of HpaII and Hha1 sites in DNA isolated from the …

DNA methylation and cancer

PC Taberlay, PA Jones - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
… aberrant DNA methylation patterns in carcinogenesis. … of DNA methylation events in cancer
is currently the best characterized epigenetic aberration in disease [2]. DNA methylation is a …

DNA methylation in development and human disease

S Gopalakrishnan, BO Van Emburgh… - … Molecular Mechanisms of …, 2008 - Elsevier
… An important link between histone H3K9 methylation and DNA methylation in mammals was
… required for recruiting Dnmt3b-dependent DNA methylation to pericentromeric repeats (Fig. …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… This loss in DNA methylation observed during aging may be due to the insufficient … of DNA
methylation across an increasing number of cell divisions (44), which ties similar methylation

[HTML][HTML] DNA methylation in metabolic disorders

R Barres, JR Zierath - The American journal of clinical nutrition, 2011 - Elsevier
… factors, possibly through DNA methylation, may play a … DNA methylation in the memory of
metabolic impairments. The purpose of this article was to consider the role of DNA methylation

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
DNA methylation do not distinguish between them, and so for the purposes of this review, all
such modifications to DNA will be referred to as ‘DNA methylation… between DNA methylation

DNA methylation and breast cancer

M Szyf, P Pakneshan, SA Rabbani - Biochemical pharmacology, 2004 - Elsevier
… of DNA methylation in controlling gene expression programs required for both deregulated
growth and metastasis and propose that different facets of the DNA methylation machinery …

Methods of DNA methylation analysis

L Shen, RA Waterland - Current Opinion in Clinical Nutrition & …, 2007 - journals.lww.com
… This review focuses on methods for studying the epigenetic mechanism DNA methylation. …
-specific DNA methylation and development of various approaches to study DNA methylation

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
… because H3K4 methylation is anticorrelated with DNA methylation, a … methylation. Several
recent findings suggest that Piwi-interacting RNAs (piRNAs) target de novo DNA methylation

Functions of DNA methylation: islands, start sites, gene bodies and beyond

PA Jones - Nature reviews genetics, 2012 - nature.com
… -scale mapping of methylation, we can evaluate DNA methylation in different genomic … of
DNA methylation seems to vary with context, and the relationship between DNA methylation