… of DNA methylation-based biomarkers. A number of excellent reviews have been published
recently on methylation and … Besides cancer, DNA methylation also appears to be useful for …

… After the HEP pilot study 6 , we sought to establish DNA methylation reference profiles for
three human chromosomes from a representative number of healthy human tissues and …

… Studies have detected cancer-specific methylation in stool (… The use of aberrant methylation
as a marker is likely to be … promoter methylation and the expanding use of DNA methylation …

… The pattern of DNA methylation plays an important role in regulating different genome …
that DNA methylation is a reversible biochemical process, we purified a DNA demethylase from …

… the role of DNA methylation in both development and disease states [6, 7]. Detection of DNA
methylation is based on the ability to distinguish cytosine from 5mC in the DNA sequence. …

… DNA methylation is a covalent chromatin modification, characterized by the biochemical
addition of a methyl group (-CH3) to cytosine nucleotides via a DNA … the latter, DNA methylation …

… and examples of integrating DNA methylation data with other … advanced topics in DNA
methylation measurement and data … of mechanisms linking DNA methylation to cellular function. …

… Three possible states of methylation: fully methylated, half-methylated, and unmethyl…
methylation occurs rarely; most DNA methylation is maintenance-type methylation following DNA …

… In this Opinion article, we summarize how changes in DNA methylation occur … DNA
methylation changes in a site-specific manner and highlight a model in which region-specific DNA …

… as another approach in DNA methylation profiling. We will discuss this methodology and its
… in studying DNA methylation in a later section. Some of the representative DNA methylation …