过去一年中添加的文章,按日期排序

Genome-wide RNA-seq, DNA methylation and small RNA-seq analysis unraveled complex gene regulatory networks in psoriasis pathogenesis

S Laha, S Das, U Banerjee, T Ganguly, S Senapati… - Gene, 2024 - Elsevier
18 天前 - … Our multi-omics analysis identified the genes and biological … STAT signaling, were
found to be regulated by both miRNAs and … and miRNAs of a complex disease with reversible

PHARMACOLOGICAL TARGETING OF FGFR IN METASTATIC BREAST CANCER IS AUGMENTED BY DNMT1 INHIBITION

MG Ayers - 2024 - hammer.purdue.edu
49 天前 - … with inhibition of DNMT1 using the reversible inhibitor GSK3484862. We used our
in vivo … Using an approach of limiting cellular plasticity through DNA methylation inhibition …

Functional effects of epigenetic alterations: towards targeted epigenetic treatment of breast cancer

J Ankill - 2024 - duo.uio.no
95 天前 - methylation has a regulatory role in estrogen signaling in … frequent alterations in
DNA methylation occurring in cancer … Our results show that reversing epigenetic alterations in …

Epigenetic reprogramming of mtDNA and its etiology in mitochondrial diseases

A Kumar, A Choudhary, A Munshi - Journal of Physiology and …, 2024 - Springer
100 天前 - … Epigenetic changes are reversible and therefore … and dysregulation of specific
signaling pathways. However, this area … DNA methylation of the nuclear genome is a well-known …

Catecholamine treatment induces reversible heart injury and cardiomyocyte gene expression

C Bode, S Preissl, L Hein, A Lother - Intensive Care Medicine …, 2024 - Springer
132 天前 - DNA methylation-guided analysis of enhancer regions identified immediate …
reversible after discontinuation of catecholamine treatment. Crosstalk with endothelin signaling and …

Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder

E Zillich, H Belschner, D Avetyan, D Andrade-Brito… - medRxiv, 2024 - medrxiv.org
149 天前 - … drugs as most potent in reversing the CUD 51 expression … signaling, and
neurogenesis as important 323 biological processes in CUD 324 The integration of DNA methylation

m6A RNA Methylation and Implications for Hepatic Lipid Metabolism

X Ming, S Chen, H Li, Y Wang, L Zhou, Y Lv - DNA and Cell Biology, 2024 - liebertpub.com
155 天前 - … (SREBP-1c) signaling pathway, which upregulated the … biological function of m6A
RNA methylation catalyzed by related enzymes. m6A modification is a dynamic and reversible

[HTML][HTML] Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid

G Carswell, J Chamberlin, BD Bennett… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
155 天前 - … our ability to recognize biological signatures of disease. Here, … gene signatures and
pathways reversed patterns later in … , such as cellular signaling, regulation and metabolism, …

Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP

X Shen, M Li, Y Li, Y Jiang, K Niu, S Zhang, X Lu… - Chinese Medicine, 2024 - Springer
164 天前 - … that BZBS treatment effectively reversed the age-related … , while concurrently impairing
insulin signaling in muscle and … liver DNA methylation clock to estimate biological age of …

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control

G da Silva Feltran, AF de Andrade… - Cell biology … - pubmed.ncbi.nlm.nih.gov
164 天前 - methylation profile, considering the methylation/hydroxymethylation ratio. CpG
methylation is a reversible process regulated by DNA … Specifically, we measured the methylation