2 天前 - … an important role in the … as DNA methylation, group protein modification, non-encoding
RNA-mediated regulation, etc., play a key role in AML and become potential treatment …

11 天前 - … to pancreatic tumor cell chemotherapy resistance has not been addressed.
Herein, we showed that PRLR downregulation induced by DNA methylation contributes to …

11 天前 - … DNA methylation, aiming to revert brain tumor cells to a more differentiated state.
Pharmacological inhibition of DNA methyltransferases is … DNMT1 inhibitor decitabine slowed …

20 天前 - … that pancreatic cancer is an epigenetic disease, … DNA methylation [14]. Recent
studies have been suggested that aberrant DNA methylation can affect the sensitivity of cancers …

27 天前 - … DNA methylation and blocking PD-L1, thus providing new … This study aims to
achieve epigenetic therapy of HCC by … targeted delivery DNMT1 inhibitor Dec. The proposal of a …

33 天前 - … epigenetic-targeted therapies, such as histone deacetylase inhibitors and DNA
methyltransferase inhibitors… associated epigenetic alterations and improving treatment outcomes…

43 天前 - … methylation status in treated Weri-Rb-1, shedding a new … the epigenetic therapy
and on the role of this therapeutic … such as the DNA methyltransferase inhibitor decitabine (5-…

56 天前 - … Taken together, these findings suggest that DNA methylation is involved in the
downregulation of LINC00987 in LUAD in vitro. Building upon the DNA methylation data, we …

57 天前 - … Epigenetic modifiers loosen the packing of chromatin by inhibiting DNA methylation
and histone deacetylation and thus permit the expression of genes that usually remain …

58 天前 - … Epigenetic mechanisms per se (DNA methylation and … of the epigenetic regulators
involved in these key tumor … the use of epigenetic therapies or to propose new strategies. We …