Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral
replication and persistence. Several DNA tumor viruses modulate host DNA
methyltransferases for epigenetic dysregulation of immune-related gene expression in host
cells. The host immune responses suppressed by virus-induced aberrant DNA methylation
are also frequently involved in antitumor immune responses. Here, we describe viral
mechanisms and virus–host interactions by which DNA tumor viruses regulate host DNA …