… DOCK8 are … Dock8 deficiency, which have revealed how DOCK8 regulates T and B cell
numbers and functions. The results of these studies help to explain how the absence of DOCK8 …

… This review will examine our current understanding of DOCK8 function in immune cells…
DOCK8 deficiency, and highlight the emergence of a family of DOCK-related immune deficiencies…

… Mutations in DOCK8 result in autosomal recessive Hyper-IgE … survey of patients with DOCK8
mutations, focused on clinical … of the clinical phenotype of DOCK8 deficiency in the largest …

… We describe seven Turkish children with DOCK8 deficiency … Patients had homozygous
mutations in DOCK8 that altered … family members showed that DOCK8 deficiency is a fully …

… load of viral disease in DOCK8 deficiency. This may be caused … after haploidentical HSCT
in DOCK8 deficiency is inferior. … after MMFD HSCT in DOCK8 deficiency is in line with recent …

… Besides lymphopenia, DOCK8 deficiency has manifestations … DOCK8 deficiency suggests
that these cancers may be due to impaired tumor surveillance. It is also possible that DOCK8 …

… DOCK8 deficiency is a newly described primary immune deficiency resulting in profound …
Although little is known about the DOCK8 protein, it resembles other atypical guanine …

… , and patients with DOCK8 deficiency exhibit decreased numbers and … In this report, we
highlight the capacity of DOCK8 deficiency to … the vital function of DOCK8 in immunoregulation. …

… that mutations in DOCK8 account for nearly … DOCK8 deficiency. We delineate the key
cutaneous manifestations and highlight the similarities and differences between DOCK8 deficiency …

… of T cells from DOCK8-deficient humans To explore the effects of DOCK8 deficiency on T
cells, we first analyzed peripheral blood T cells from six DOCK8-deficient patients from five …