Decanalization of immune response during the dispersion of modern humans: The relationships of genetic diversity in immune system genes and climatic and …
Allele frequencies of sevengenes contributing to cellular immune response to parasitic
infections, polarization of immune response to Th2 type and associated with atopic and
allergic phenotypes was studied in 15 World popu I ations. Selection of genes and
populations under study was based on the hypothesis of a shift in preferential immune
response balance from Th2 to Th1 type during migration of modern humans from equatorial
Africa to moderate and arctic climate regions. It is suggested that this shift was due to natural …
infections, polarization of immune response to Th2 type and associated with atopic and
allergic phenotypes was studied in 15 World popu I ations. Selection of genes and
populations under study was based on the hypothesis of a shift in preferential immune
response balance from Th2 to Th1 type during migration of modern humans from equatorial
Africa to moderate and arctic climate regions. It is suggested that this shift was due to natural …
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